Article
Identification of hepatitis C virus genotype 3 by a commercial assay challenged by natural polymorphisms detected in Spain from patients with diverse origins.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 May 2016
Saludes Verónica, Quer Josep, Gregori Josep, Bascuñana Elisabet, García-Cehic Damir, Esteban Juan Ignacio, Ausina Vicente, Martró Elisa
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) genotyping is crucial in clinical practise for determining the type and duration of antiviral therapy. Between 2009 and 2014, 24 (7.95%) of all HCV genotype 3 (HCV-3) cases obtained indeterminate results via the RealTime HCV Genotype II assay (Abbott) at a tertiary care center in Spain. HCV-3 is the second most common genotype worldwide. Moreover, it has been associated with a...
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