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Article

Genomic and transcriptomic analysis of the streptomycin-dependent Mycobacterium tuberculosis strain 18b.

BMC genomics - 5 Mar 2016

Benjak Andrej, Uplekar Swapna, Zhang Ming, Piton Jérémie, Cole Stewart T, Sala Claudia

Abstract excerpt

BACKGROUND: The ability of Mycobacterium tuberculosis to establish a latent infection (LTBI) in humans confounds the treatment of tuberculosis. Consequently, there is a need to discover new therapeutic agents that can kill M. tuberculosis both during active disease and LTBI. The streptomycin-dependent strain of M. tuberculosis, 18b, provides a useful tool for this purpose since upon removal of streptomycin (STR)...

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Share to Comparative Genomic Hybridization
Share to Genome, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26944551
DOI: 10.1186/s12864-016-2528-2
PMCID: PMC4779234

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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