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Article

Natural Genetic Variation Differentially Affects the Proteome and Transcriptome in Caenorhabditis elegans.

Molecular & cellular proteomics : MCP - 1 May 2016

Kamkina Polina, Snoek L Basten, Grossmann Jonas, Volkers Rita J M, Sterken Mark G, Daube Michael, Roschitzki Bernd, Fortes Claudia, Schlapbach Ralph, Roth Alexander, von Mering Christian, Hengartner Michael O, Schrimpf Sabine P, Kammenga Jan E

Abstract excerpt

Natural genetic variation is the raw material of evolution and influences disease development and progression. An important question is how this genetic variation translates into variation in protein abundance. To analyze the effects of the genetic background on gene and protein expression in the nematode Caenorhabditis elegans, we quantitatively compared the two genetically highly divergent wild-type strains N2...

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Identifiers

PMID: 26944343
DOI: 10.1074/mcp.M115.052548
PMCID: PMC4858947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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