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Article

The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10.

Molecular and cellular biology - 1 Jan 2010

Bestwick Megan, Khalimonchuk Oleh, Pierrel Fabien, Winge Dennis R

Abstract excerpt

Saccharomyces cerevisiae cells lacking the cytochrome c oxidase (CcO) assembly factor Coa2 are impaired in Cox1 maturation and exhibit a rapid degradation of newly synthesized Cox1. The respiratory deficiency of coa2 Delta cells is suppressed either by the presence of a mutant allele of the Cox10 farnesyl transferase involved in heme a biosynthesis or through impaired proteolysis by the disruption of the...

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Identifiers

PMID: 19841065
DOI: 10.1128/MCB.00869-09
PMCID: PMC2798283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10.PMID 19841065Read ↗

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