Article
The Impact of Selection, Gene Conversion, and Biased Sampling on the Assessment of Microbial Demography.
Molecular biology and evolution - 1 Jul 2016
Lapierre Marguerite, Blin Camille, Lambert Amaury, Achaz Guillaume, Rocha Eduardo P C
Abstract excerpt
Recent studies have linked demographic changes and epidemiological patterns in bacterial populations using coalescent-based approaches. We identified 26 studies using skyline plots and found that 21 inferred overall population expansion. This surprising result led us to analyze the impact of natural selection, recombination (gene conversion), and sampling biases on demographic inference using skyline plots and...
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