Article
CYP1A1, GSTM1, GSTT1 and TP53 Polymorphisms and Risk of Gallbladder Cancer in Bolivians.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Sakai Kazuaki, Loza Ernesto, Roig Guido Villa-Gomez, Nozaki Ryoko, Asai Takao, Ikoma Toshikazu, Tsuchiya Yasuo, Kiyohara Chikako, Yamamoto Masaharu, Nakamura Kazutoshi
Abstract excerpt
The Plurinational State of Bolivia (Bolivia) has a high incidence rate of gallbladder cancer (GBC). However, the genetic and environmental risk factors for GBC development are not well understood. We aimed to assess whether or not cytochrome P450 (CYP1A1), glutathione S-transferase mu 1 (GSTM1), theta 1 (GSTT1) and tumor suppressor protein p53 (TP53) genetic polymorphisms modulate GBC susceptibility in Bolivians....
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