Article
Association between glutathione S-transferase M1 null genotype and risk of gallbladder cancer: a meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014
Sun Hong-Li, Han Bing, Zhai Hong-Peng, Cheng Xin-Hua, Ma Kai
Abstract excerpt
Glutathione S-transferases (GSTs) are a family of enzymes which are involved in the detoxification of potential carcinogens. Glutathione S-transferase M1 (GSTM1) null genotype can impair the enzyme activity of GSTs and is suspected to increase the susceptibility to gallbladder cancer. Previous studies investigating the association between GSTM1 null genotype and risk of gallbladder cancer reported inconsistent...
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