Article
Mutation of MED12 is not a frequent occurrence in prostate cancer of Korean patients.
Asian journal of andrology - 1 Jan 2000
Yoon Nara, Lim Sharon, Kang So Young, Kwon Ghee Young, Jeon Hwang Gyun, Jeong Byong Chang, Seo Seong Il, Jeon Seong Soo, Lee Hyun Moo, Choi Han Yong
Abstract excerpt
Prostate cancer is one of the major health care problems, but the molecular pathogenesis has been relatively insufficiently elucidated. Recently, whole exome sequencing of prostate cancer identified recurrent mutations involving MED12 in Caucasian patients, which finding was not reproduced in one subsequent study by Sanger sequencing. Thus, we investigated mutation status of MED12 in exons 2 and 26 by Sanger...
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