Article
A kidney-specific genome-scale metabolic network model for analyzing focal segmental glomerulosclerosis.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2016
Sohrabi-Jahromi Salma, Marashi Sayed-Amir, Kalantari Shiva
Abstract excerpt
Focal Segmental Glomerulosclerosis (FSGS) is a type of nephrotic syndrome which accounts for 20 and 40 % of such cases in children and adults, respectively. The high prevalence of FSGS makes it the most common primary glomerular disorder causing end-stage renal disease. Although the pathogenesis of this disorder has been widely investigated, the exact mechanism underlying this disease is still to be discovered....
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