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Identification of diagnostic biomarkers and potential therapeutic drugs in focal segmental glomerulosclerosis with metabolic syndrome by integrating bioinformatics and machine learning

2024-12-24

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<title>Abstract</title> <p><bold>Purpose</bold> Immune system dysregulation plays a pivotal role in focal segmental glomerulosclerosis (FSGS) and metabolic syndrome (MS). This study aimed to identify core diagnostic genes and potential therapeutic drugs for FSGS patients with MS. <bold>Methods</bold> We obtained two FSGS and one MS datasets from the GEO database. DEGs and module gene were identified via Limma and...

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Literature Corpus work
e05d443f-dacf-50ec-ab70-c1a7b6d6d96c
DOI
10.21203/rs.3.rs-5609059/v1
Open publication

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Identification of diagnostic biomarkers and potential therapeutic drugs in focal segmental glomerulosclerosis with metabolic syndrome by integrating bioinformatics and machine learningDOI 10.21203/rs.3.rs-5609059/v1
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