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Article

Pathogenesis and therapy of focal segmental glomerulosclerosis: an update.

Pediatric nephrology (Berlin, Germany) - 1 Jul 2011

Gbadegesin Rasheed, Lavin Peter, Foreman John, Winn Michelle

Abstract excerpt

Focal and segmental glomerulosclerosis (FSGS) is an important cause of steroid-resistant nephrotic syndrome in adults and children. It is responsible for 5-20% of all cases of end-stage kidney disease (ESKD) in the United States. The pathogenesis of FSGS has not been fully elucidated; however, data from molecular studies of familial cases in the last two decades suggest that FSGS is a defect of the podocyte. The...

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Share to Genetic Predisposition to Disease
Share to Glomerulosclerosis, Focal Segmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21110043
DOI: 10.1007/s00467-010-1692-x
PMCID: PMC3624015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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