Article
Sjögren's syndrome patients with ectopic germinal centers present with a distinct salivary proteome.
Rheumatology (Oxford, England) - 1 Jun 2016
Delaleu Nicolas, Mydel Piotr, Brun Johan G, Jonsson Malin V, Alimonti Andrea, Jonsson Roland
Abstract excerpt
OBJECTIVE: Clinical expression of SS shows considerable interpatient heterogeneity. Thus, the aim of this study was to assess whether individual salivary proteomic profiles provide a framework for identification of disease-phenotype-driven biomarker signatures. METHODS: Using a 187-plex capture antibody-based assay, proteomic biomarker profiles from unstimulated whole saliva were generated from a SS-cohort...
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