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Article

High Fidelity Between Saliva Proteomics and the Biologic State of Salivary Glands Defines Biomarker Signatures for Primary Sjögren's Syndrome

29 Dec 2014

Abstract excerpt

OBJECTIVE: Dependence on invasive procedures for classification of patients with Sjögren's syndrome (SS) hampers timely diagnosis and suitable patient followup. The aim of this study was to recapitulate the diagnosis of SS through noninvasive means and to define the biologic state of SS patients' salivary glands. METHODS: Using a 187-plex capture antibody-based assay, salivary proteomic biomarker profiles were...

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PMID: 25545990
DOI: 10.1002/art.39015

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