Article
Genotyping of colorectal cancer for cancer precision medicine: Results from the IPH Center for Molecular Pathology.
Genes, chromosomes & cancer - 1 Jun 2016
Jesinghaus Moritz, Pfarr Nicole, Endris Volker, Kloor Matthias, Volckmar Anna-Lena, Brandt Regine, Herpel Esther, Muckenhuber Alexander, Lasitschka Felix, Schirmacher Peter, Penzel Roland, Weichert Wilko, Stenzinger Albrecht
Abstract excerpt
Cancer precision medicine has opened up new avenues for the treatment of colorectal cancer (CRC). To fully realize its potential, high-throughput sequencing platforms that allow genotyping beyond KRAS need to be implemented and require performance assessment. We comprehensively analyzed first-year data of 202 consecutive formalin-fixed paraffin embedded (FFPE) CRC samples for which prospective genotyping at our...
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