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Article

Clinical Manifestations and Gene Expression in Patients with Conventional Papillary Thyroid Carcinoma Carrying the BRAF(V600E) Mutation and BRAF Pseudogene.

Thyroid : official journal of the American Thyroid Association - 1 May 2016

Lin Jiunn-Diann, Fu Shuai-Shuai, Chen Jui-Yu, Lee Chen-Hsen, Chau Wing-Keung, Cheng Chao-Wen, Wang Yuan-Hung, Lin Yuh-Feng, Fang Wen-Fang, Tang Kam-Tsun

Abstract excerpt

BACKGROUND: The association of BRAF(V600E) with the clinical manifestations of papillary thyroid carcinoma (PTC) remains controversial. Recent studies have shown that the BRAF pseudogene can activate the MAPK pathway and induce tumorigenesis. This study investigated the association of BRAF(V600E), the BRAF pseudogene, and their mRNA levels with clinical features and thyroid-specific gene expression in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26914762
DOI: 10.1089/thy.2015.0044

Genes

BRAF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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