Article
Frontotemporal dementia: insights into the biological underpinnings of disease through gene co-expression network analysis.
Molecular neurodegeneration - 24 Feb 2016
Ferrari Raffaele, Forabosco Paola, Vandrovcova Jana, Botía Juan A, Guelfi Sebastian, Warren Jason D, Momeni Parastoo, Weale Michael E, Ryten Mina, Hardy John
Abstract excerpt
BACKGROUND: In frontotemporal dementia (FTD) there is a critical lack in the understanding of biological and molecular mechanisms involved in disease pathogenesis. The heterogeneous genetic features associated with FTD suggest that multiple disease-mechanisms are likely to contribute to the development of this neurodegenerative condition. We here present a systems biology approach with the scope of i) shedding...
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