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Article

Iron induces cancer stem cells and aggressive phenotypes in human lung cancer cells.

American journal of physiology. Cell physiology - 1 May 2016

Chanvorachote Pithi, Luanpitpong Sudjit

Abstract excerpt

Evidence has accumulated in support of the critical impact of cancer stem cells (CSCs) behind the chemotherapeutic failure, cancer metastasis, and subsequent disease recurrence and relapse, but knowledge of how CSCs are regulated is still limited. Redox status of the cells has been shown to dramatically influence cell signaling and CSC-like aggressive behaviors. Here, we investigated how subtoxic concentrations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26911281
DOI: 10.1152/ajpcell.00322.2015

Genes

SOX9
ABCG2
SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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