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Differential Effect of Cytomegalovirus Infection with Age on the Expression of CD57, CD300a, and CD161 on T-Cell Subpopulations

2 Jun 2017

Abstract excerpt

Immunosenescence is a progressive deterioration of the immune system with ageing. It affects both innate and adaptive immunity limiting the response to pathogens and to vaccines. As chronic cytomegalovirus (CMV) infection is probably one of the major driving forces of immunosenescence, and its persistent infection results in functional and phenotypic changes to the T-cell repertoire, the aim of this study was to...

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PMID: 28626460
DOI: 10.3389/fimmu.2017.00649

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