Association between Mutation and Expression of TP53 as a Potential Prognostic Marker of Triple-Negative Breast Cancer

Abstract excerpt

PURPOSE: status as a prognostic and predictive marker of triple-negative breast cancer (TNBC). MATERIALS AND METHODS: alteration and clinical outcomes of TNBC patients. RESULTS: deletion mutation indicated poor prognosis (5Y DRFS: low vs. high, 91.7% vs. 75.0%; p=0.316). CONCLUSION: mutation and expression indicates a potential prognostic marker of TNBC; hence both DNA sequencing and mRNA expression analysis may...

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