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Article

Polymorphisms of the FTO and MTHFR genes and vascular, inflammatory and metabolic marker levels in postmenopausal women.

Journal of endocrinological investigation - 1 Aug 2016

Chedraui P, Pérez-López F R, Escobar G S, Espinoza-Caicedo J A, Montt-Guevara M, Genazzani A R, Simoncini T

Abstract excerpt

OBJECTIVE: To determine the prevalence of three single nucleotide polymorphisms (SNPs) in postmenopausal women with and without the metabolic syndrome (METS) and to explore levels of circulating biomarkers of inflammation, vascular and metabolic dysfunction according to SNP genotypes. METHODS: DNA was extracted from the whole blood of 192 natural postmenopausal women (40 to 65 years) screened for the METS and...

Read the complete abstract on PubMed

Topics

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 26902996
DOI: 10.1007/s40618-016-0443-7

Genes

FTO
MTHFR
TNF

Variants

rs9939609
rs9939609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polymorphisms of the FTO and MTHFR genes and vascular, inflammatory and metabolic marker levels in postmenopausal women.PMID 26902996Read ↗

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Association of the rs9939609 gene variant in FTO with insulin resistance, cardiovascular risk factor and serum adipokine levels in obese patients.Semantic proximity Read ↗

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The FTO gene polymorphism (rs9939609) is associated with metabolic syndrome in morbidly obese subjects from southern Italy.Semantic proximity Read ↗

Relation of the rs9939609 gene variant in FTO with metabolic syndrome in obese female patients.Semantic proximity Read ↗

Association of genetic variants with the metabolic syndrome in 20,806 white women: The Women's Health Genome Study.Semantic proximity Read ↗

Association of rs9939609 Polymorphism with Metabolic Parameters and FTO Risk Haplotype Among Tunisian Metabolic Syndrome.Semantic proximity Read ↗

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Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index.Semantic proximity Read ↗

Fat mass and obesity-associated gene polymorphisms do not affect metabolic response to hormone therapy in healthy postmenopausal women.Semantic proximity Read ↗

The fat mass and obesity-associated (FTO) gene variant rs9939609 predicts long-term incidence of cardiovascular disease and related death independent of the traditional risk factors.Semantic proximity Read ↗

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