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Article

Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index.

PloS one - 5 Jan 2011

Zimmermann Esther, Skogstrand Kristin, Hougaard David M, Astrup Arne, Hansen Torben, Pedersen Oluf, Sørensen Thorkild I A, Jess Tine

Abstract excerpt

BACKGROUND: A recent study reported that the fatness associated A-allele of FTO rs9939609 increased plasma high sensitivity C-reactive protein (hs-CRP) levels independent of fatness. We aimed to investigate if this gene variant had fatness-independent effects on plasma hs-CRP and 10 additional ci...

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Identifiers

PMID: 21246032
DOI: 10.1371/journal.pone.0015958
PMCID: PMC3016333

Genes

FTO
CRP
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21246032-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

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Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index.PMID 21246032Read ↗

Variants in the fat mass and obesity associated (FTO) gene are associated with obesity and C-reactive protein levels in Chinese Han populations.Semantic proximity Read ↗

Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism--the Finnish Diabetes Prevention Study.Semantic proximity Read ↗

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness.Semantic proximity Read ↗

Association of the FTO rs9939609 single nucleotide polymorphism with C-reactive protein levels.Semantic proximity Read ↗

Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men.Semantic proximity Read ↗

Influence of FTO variants on obesity, inflammation and cardiovascular disease risk biomarkers in Spanish children: a case-control multicentre study.Semantic proximity Read ↗

The Influence of FTO, FABP2, LEP, LEPR, and MC4R Genes on Obesity Parameters in Physically Active Caucasian Men.Semantic proximity Read ↗

Association of the rs9939609 gene variant in FTO with insulin resistance, cardiovascular risk factor and serum adipokine levels in obese patients.Semantic proximity Read ↗

The common FTO variant rs9939609 is not associated with BMI in a longitudinal study on a cohort of Swedish men born 1920-1924.Semantic proximity Read ↗

The FTO obesity gene. Genotyping and gene expression analysis in morbidly obese patients.Semantic proximity Read ↗

Replication of the association of common rs9939609 variant of FTO with increased BMI in an Australian adult twin population but no evidence for gene by environment (G x E) interaction.Semantic proximity Read ↗

The FTO gene polymorphism (rs9939609) is associated with metabolic syndrome in morbidly obese subjects from southern Italy.Semantic proximity Read ↗

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