Article
The FTO gene polymorphism (rs9939609) is associated with metabolic syndrome in morbidly obese subjects from southern Italy.
Molecular and cellular probes - 1 Aug 2014
Liguori Rosario, Labruna Giuseppe, Alfieri Andreina, Martone Domenico, Farinaro Eduardo, Contaldo Franco, Sacchetti Lucia, Pasanisi Fabrizio, Buono Pasqualina
Abstract excerpt
Gene variants in MC4R, SIRT1 and FTO are associated with severe obesity and metabolic impairment in Caucasians. We investigated whether common variants in these genes are associated with metabolic syndrome (MetS) in a large group of morbidly obese young adults from southern Italy. One thousand morbidly obese subjects (62% women, mean body mass index 46.5 kg/m(2), mean age 32.6 years) whose families had lived in...
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