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Article

Range of CD4-Bound Conformations of HIV-1 gp120, as Defined Using Conditional CD4-Induced Antibodies.

Journal of virology - 1 May 2016

Kaplan Gilad, Roitburd-Berman Anna, Lewis George K, Gershoni Jonathan M

Abstract excerpt

UNLABELLED: The HIV envelope binds cellular CD4 and undergoes a range of conformational changes that lead to membrane fusion and delivery of the viral nucleocapsid into the cellular cytoplasm. This binding to CD4 reveals cryptic and highly conserved epitopes, the molecular nature of which is still not fully understood. The atomic structures of CD4 complexed with gp120 core molecules (a form of gp120 in which the...

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Source

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Identifiers

PMID: 26889042
DOI: 10.1128/JVI.03206-15
PMCID: PMC4836356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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