Article
Quantitative proteomic analysis identifies new effectors of FOXM1 involved in breast cancer cell migration.
International journal of clinical and experimental pathology - 1 Jan 2015
Ye Xiaojuan, Zhang Yi, He Bin, Meng Yuesheng, Li Yandong, Gao Yong
Abstract excerpt
The Forkhead Box M1 (FOXM1) transcription factor plays important roles in tumorigenesis and tumor metastasis in multiple human carcinomas. However, the underlying mechanisms for FOXM1 function remain to be classified. In the present study, we employed quantitative proteomic approach to search new downstream targets of FOXM1 in breast cancer MDA-MB-231 cells. A total of 4125 proteins were identified and quantified...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
