Article
Global identification of miR-373-regulated genes in breast cancer by quantitative proteomics.
Proteomics - 1 Mar 2011
Yan Guang-Rong, Xu Song-Hui, Tan Zi-Lu, Liu Langxia, He Qing-Yu
Abstract excerpt
Although microRNAs (miRNAs) have been reported to play an important role in carcinogenesis, their molecular mechanism remains largely unknown because of our limited understanding of miRNA target genes. miR-373 was found to be capable of promoting breast cancer invasion and metastasis, but only a target gene was experimentally identified on the basis of mRNA expression analysis. In this study, we used SILAC-based...
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