MicroRNA and Multiple Myeloma: from Laboratory Findings to Translational Therapeutic Approaches

Abstract excerpt

Multiple myeloma (MM) is due to the proliferation in the bone marrow of malignant plasma cells and accounts for about 10% of all hematological tumors. MM is the natural evolution of a monoclonal gammopathy of uncertain significance. Although the introduction of novel biological agents in the clinical practice has changed the natural history of the disease, MM remains incurable. MicroRNAs (miRNAs) are short...

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