Article
Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease.
BMC genomics - 16 Feb 2016
Gupta Yask, Möller Steffen, Witte Mareike, Belheouane Meriem, Sezin Tanya, Hirose Misa, Vorobyev Artem, Niesar Felix, Bischof Julia, Ludwig Ralf J, Zillikens Detlef, Sadik Christian D, Restle Tobias, Häsler Robert, Baines John F, Ibrahim Saleh M
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that control genes at post-transcriptional level. They are essential for development and tissue differentiation, and such altered miRNA expression patterns are linked to the pathogenesis of inflammation and cancer. There is evidence that miRNA expression is genetically controlled similar to the transcription of protein-coding genes and previous...
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