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Article

Changes in cell shape are correlated with metastatic potential in murine and human osteosarcomas

12 Feb 2016

Abstract excerpt

Metastatic cancer cells for many cancers are known to have altered cytoskeletal properties, in particular to be more deformable and contractile. Consequently, shape characteristics of more metastatic cancer cells may be expected to have diverged from those of their parental cells. To examine this hypothesis we study shape characteristics of paired osteosarcoma cell lines, each consisting of a less metastatic...

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PMID: 26873952
DOI: 10.1242/bio.013409

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