Article
Viscoelastic properties of transformed cells: role in tumor cell progression and metastasis formation.
Biorheology - 1 Jan 1991
Ward K A, Li W I, Zimmer S, Davis T
Abstract excerpt
The micropipette aspiration technique was used to investigate the deformation properties of a panel of nontransformed and transformed rat fibroblasts derived from the same normal cell line. In this method, a step negative pressure is applied to the cell via a micropipette and the aspiration distance into the pipette as a function of time is determined using video techniques. A standard solid viscoelastic model...
Topics
- Animals
- Cell Line
- Cell Transformation, Neoplastic
- Elasticity
- Fibroblasts
- Models, Biological
- Neoplasm Metastasis
- Phenotype
- Rats
- Rheology
- Video Recording
- Viscosity