Article
NusA is required for ribosomal antitermination and for modulation of the transcription elongation rate of both antiterminated RNA and mRNA.
The Journal of biological chemistry - 9 May 1997
Vogel U, Jensen K F
Abstract excerpt
Ribosomal RNA (rRNA) is elongated twice as fast as mRNA in vivo due to the presence of antitermination sequences in the 5' part of the rRNA transcripts. A number of Nus factors bind to RNA polymerase at the antitermination sites and help confer resistance to Rho-dependent termination of transcription. In this paper, the effects of the nusAcs10 allele on the elongation rate of both mRNA and antiterminated RNA were...
Topics
- Alleles
- Bacterial Proteins
- Escherichia coli Proteins
- Lac Operon
- Nucleic Acid Conformation
- Peptide Elongation Factors
- RNA, Messenger
- RNA, Ribosomal
- Transcription Factors
- Transcription, Genetic
- Transcriptional Elongation Factors