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Article

The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells.

Oncotarget - 22 Mar 2016

Faddaoui Adnen, Bachvarova Magdalena, Plante Marie, Gregoire Jean, Renaud Marie-Claude, Sebastianelli Alexandra, Gobeil Stephane, Morin Chantale, Macdonald Elizabeth, Vanderhyden Barbara, Bachvarov Dimcho

Abstract excerpt

The molecular basis of epithelial ovarian cancer (EOC) dissemination is still poorly understood. Previously, we identified the mannose receptor LY75 gene as hypomethylated in high-grade (HG) serous EOC tumors, compared to normal ovarian tissues. LY75 represents endocytic receptor expressed on dendritic cells and so far, has been primarily studied for its role in antigen processing and presentation. Here we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26871602
DOI: 10.18632/oncotarget.7288
PMCID: PMC4924702

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MET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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