Article
Autoantibodies directed to centromere protein F in a patient with BRCA1 gene mutation.
BMC research notes - 11 Feb 2016
Moghaddas Fiona, Joshua Fredrick, Taylor Roberta, Fritzler Marvin J, Toh Ban Hock
Abstract excerpt
BACKGROUND: Autoantibodies directed to centromere protein F were first reported in 1993 and their association with malignancy has been well documented. CASE: We present the case of a 48-year-old Caucasian female with a BRCA1 gene mutation associated with bilateral breast cancer. Antinuclear autoantibody immunofluorescence performed for workup of possible inflammatory arthropathy showed a high titre cell cycle...
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