Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HOX transcription factors are potential targets and markers in malignant mesothelioma

11 Feb 2016

Abstract excerpt

BACKGROUND: The HOX genes are a family of homeodomain-containing transcription factors that determine cellular identity during development and which are dys-regulated in some cancers. In this study we examined the expression and oncogenic function of HOX genes in mesothelioma, a cancer arising from the pleura or peritoneum which is associated with exposure to asbestos. METHODS: We tested the sensitivity of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Developmental Biology and Gene Regulation
Share to Occupational and environmental lung diseases
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26867567
DOI: 10.1186/s12885-016-2106-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HOX transcription factors are potential targets and markers in malignant mesotheliomaPMID 26867567Read ↗

ZDHHC8 knockdown enhances radiosensitivity and suppresses tumor growth in a mesothelioma mouse modelSemantic proximity Read ↗

Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cellsSemantic proximity Read ↗

DNA repair and damage pathways in mesothelioma development and therapySemantic proximity Read ↗

Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in miceSemantic proximity Read ↗

Update on the molecular biology of malignant mesotheliomaSemantic proximity Read ↗

Mesothelioma patient derived tumor xenografts with defined BAP1 mutations that mimic the molecular characteristics of human malignant mesothelioma.Semantic proximity Read ↗

Mesothelioma: recent highlightsSemantic proximity Read ↗

Matrix Metalloproteinases as Biomarkers and Treatment Targets in Mesothelioma: A Systematic Review.Semantic proximity Read ↗

HMGB1 as a Potential Biomarker and Therapeutic Target for Malignant MesotheliomaSemantic proximity Read ↗

CDKN2A Determines Mesothelioma Cell Fate to EZH2 InhibitionSemantic proximity Read ↗

PBX3 is an important cofactor of HOXA9 in leukemogenesisSemantic proximity Read ↗

Apoptosis Induced by Piroxicam plus Cisplatin Combined Treatment Is Triggered by p21 in MesotheliomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.