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Mannose Binding Lectin Gene Mutations Are Associated With Progression of Liver Disease in Chronic Hepatitis B Infection

1 Apr 1999

Abstract excerpt

Mannose-binding lectin (MBL) plays an important role in immune defense. We examined the MBL gene mutations and MBL levels in Chinese hepatitis B and hepatitis C patients with and without symptomatic cirrhosis. We recruited 190 hepatitis B and C patients, and 117 normal Chinese as controls. Serum MBL levels were measured by enzyme-linked immunosorbent assay. MBL gene mutation at codons 52, 54, and 57 was detected...

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PMID: 10094971
DOI: 10.1002/hep.510290417

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