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Article

Genotoxic properties of XLR-11, a widely consumed synthetic cannabinoid, and of the benzoyl indole RCS-4.

Archives of toxicology - 1 Dec 2016

Ferk Franziska, Gminski Richard, Al-Serori Halh, Mišík Miroslav, Nersesyan Armen, Koller Verena J, Angerer Verena, Auwärter Volker, Tang Tao, Arif Ali Talib, Knasmüller Siegfried

Abstract excerpt

Aim of this study was the investigation of the genotoxic properties of XLR-11 [1-(5-fluoropentyl)-1H-indol-3-yl](2,2,3,3-tetramethylcyclopropyl)methanone, a widely consumed synthetic cannabinoid (SC), and of the benzoyl indole RCS-4 (4-methoxyphenyl)(1-pentyl-1H-indol-3-yl)methanone). We characterized the DNA-damaging properties of these drugs in different experimental systems. No evidence for induction of gene...

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PMID: 26856714
DOI: 10.1007/s00204-016-1664-4
PMCID: PMC5104816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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