Article
[Preliminary research on opioid mutagenicity].
Przeglad lekarski - 1 Jan 2003
Gorazd Monika, Kamenczak Aleksandra, Pach Janusz, Schmager Jan, Wronka Iwona
Abstract excerpt
The aim of the study was a preliminary recognition of genotoxic effect of methadone, using a culture of lymphocytes obtained from the blood of 23 opiate dependent patients from methadone maintenance treatment programme conducted at the Department of Clinical Toxicology of Jagiellonian University Medical College. The micronuclei (MN) occurrence and the number of sister chromatids exchange in methaphasal plate were...
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