Article
Frequency of HLA-DRB1 and HLA-DQB1 Alleles and Haplotype Association in Syrian Population.
Immunological investigations - 1 Jan 2016
Jazairi Batoul, Khansaa Issam, Ikhtiar Adnan, Murad Hossam
Abstract excerpt
The study of Human Leukocyte Antigen (HLA) system is very important in health and diseases. As the HLA loci are the most polymorphic in the human genome, it plays a very important role in the immune responses to self and nonself antigens. In the light of the growing importance of typing the HLA alleles in transplantation, autoimmune diseases, cancer, and many other diseases, we studied 225 unrelated healthy...
Topics
- Alleles
- Cluster Analysis
- Evolution, Molecular
- Female
- Gene Frequency
- Genetics, Population
- Genotype
- HLA-DQ beta-Chains
- HLA-DRB1 Chains
- Haplotypes
- Humans
- Male
- Principal Component Analysis
- Racial Groups
- Syria