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Article

Phenotypic, genotypic, and functional characterization of normal and acute myeloid leukemia-derived marrow endothelial cells.

Experimental hematology - 1 May 2016

Pizzo Russell J, Azadniv Mitra, Guo Naxin, Acklin Joshua, Lacagnina Kimberly, Coppage Myra, Liesveld Jane L

Abstract excerpt

In addition to participation in homing, egress, and transmigration of hematopoietic cells, marrow endothelium also contributes to cell proliferation and survival. Endothelial cells from multiple vascular beds are able to prevent spontaneous or therapy-induced apoptosis in acute myelogenous leukemia (AML) blasts. Marrow-derived endothelial cells from leukemia patients have not been well-characterized, and in this...

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Source

Identifiers

PMID: 26851308
DOI: 10.1016/j.exphem.2016.01.008

Genes

CXCL16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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