Article
Sugar-carrying Polystyrenes Facilitate Harvesting of APCs from MLRs: Possible Application of Sugar-carrying Polystyrenes to Immunotherapy.
Anticancer research - 1 Feb 2016
Imaizumi Akira, Onishi Hideya, Yamasaki Akio, Kawamoto Makoto, Morisaki Takashi, Goto Mitsuaki, Iwama Masamichi, Akaike Toshihiro, Hasumi Kenichiro
Abstract excerpt
Antigen-presenting cells (APCs) play a pivotal role in cancer immunotherapy. APCs in conventionally used flasks are harvested by enzymatic digestion or cell scraping for application to cancer immunotherapy. However, these methods may impair functional molecules expressed on the APC surface and reduce their effects in cancer immunotherapy. Recently, we found that APCs could be harvested by shaking at 4°C in flasks...
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