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Article

Dysfunction of WNT4/WNT5A in deciduas

5 Feb 2016

Abstract excerpt

OBJECTIVES: Preeclampsia affects 5-7% of all human pregnancies worldwide. It is characterized primarily by hypertension and proteinuria. Although the pathogenesis of preeclampsia is still not fully understood, the deficiency in decidualization is considered to have a role in this disease. WNT4 and WNT5A are highly expressed in the deciduas of mice and human beings; their deficiency causes the abnormality of mouse...

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Identifiers

PMID: 26848991
DOI: 10.1097/hjh.0000000000000851

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