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Article

Wnt/β-catenin signaling pathway in trophoblasts and abnormal activation in preeclampsia

1 Feb 2017

Abstract excerpt

Preeclampsia (PE) is one of the most common types of hypertensive disease and occurs in 3‑4% of pregnancies. There are a number of theories on the pathogenesis of PE. Abnormal differentiation of the placenta may lead to failure of trophoblast migration, shallow placenta implantation and placental ischemia/hypoxia, followed by the subsequent occurrence of PE. The Wnt/β-catenin pathway is a canonical Wnt‑signaling...

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PMID: 29067442
DOI: 10.3892/mmr.2017.6718

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