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Article

The value of molecular stratification for CEBPA(DM) and NPM1(MUT) FLT3(WT) genotypes in older patients with acute myeloid leukaemia.

British journal of haematology - 1 Feb 2016

Dickson Glenda J, Bustraan Sophia, Hills Robert K, Ali Akbar, Goldstone Anthony H, Burnett Alan K, Linch David C, Gale Rosemary E

Abstract excerpt

Older adult patients (≥60 years) with acute myeloid leukaemia (AML) are generally considered to be poor-risk and there is limited information available regarding risk stratification based on molecular characterization in this age group, particularly for the double-mutant CEBPA (CEBPA(DM) ) genotype. To investigate whether a molecular favourable-risk genotype can be identified, we investigated CEBPA, NPM1 and FLT3...

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Source

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Identifiers

PMID: 26847745
DOI: 10.1111/bjh.13873
PMCID: PMC4855634

Genes

FLT3
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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