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Article

The H3F3 K36M mutant antibody is a sensitive and specific marker for the diagnosis of chondroblastoma.

Histopathology - 1 Jul 2016

Amary M Fernanda, Berisha Fitim, Mozela Rafael, Gibbons Rebecca, Guttridge Alice, O'Donnell Paul, Baumhoer Daniel, Tirabosco Roberto, Flanagan Adrienne M

Abstract excerpt

AIMS: We recently reported that 95% of chondroblastomas harbour a p.K36M mutation in either H3F3A (chromosome 1) or H3F3B (chromosome 17), with the majority involving H3F3B. The aim of this study was to assess the expression of the K36M-mutated protein by immunohistochemistry in a large group of tumours. METHODS AND RESULTS: One thousand eight hundred and ninety-four tumours, including 85 chondroblastomas and 10...

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Identifiers

PMID: 26844533
DOI: 10.1111/his.12945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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