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Article

Replication of GWAS Coding SNPs Implicates MMEL1 as a Potential Susceptibility Locus among Saudi Arabian Celiac Disease Patients.

Disease markers - 1 Jan 2015

Saadah Omar I, Shaik Noor Ahmad, Banaganapalli Babajan, Salama Mohammed A, Al-Harthi Sameer E, Wang Jun, Shawoosh Harbi A, Alghamdi Sharifa A, Bin-Taleb Yagoub Y, Alhussaini Bakr H, Elango Ramu, Al-Aama Jumana Y

Abstract excerpt

Celiac disease (CD), a gluten intolerance disorder, was implicated to have 57 genetic susceptibility loci for Europeans but not for culturally and geographically distinct ethnic populations like Saudi Arabian CD patients. Therefore, we genotyped Saudi CD patients and healthy controls for three polymorphisms, that is, Phe196Ser in IRAK1, Trp262Arg in SH2B3, and Met518Thr in MMEL1 genes. Single locus analysis...

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Source

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Identifiers

PMID: 26843707
DOI: 10.1155/2015/351673
PMCID: PMC4710944

Genes

MMEL1
IRAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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