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Article

Two di-leucine motifs regulate trafficking and function of mouse ASIC2a.

Molecular brain - 27 Jan 2016

Wu Junjun, Leng Tiandong, Jing Lan, Jiang Nan, Chen Daijie, Hu Youjia, Xiong Zhi-Gang, Zha Xiang-ming

Abstract excerpt

BACKGROUND: Acid-sensing ion channels (ASICs) are proton-gated cation channels that mediate acid-induced responses in neurons. ASICs are important for mechanosensation, learning and memory, fear, pain, and neuronal injury. ASIC2a is widely expressed in the nervous system and modulates ASIC channel trafficking and activity in both central and peripheral systems. Here, to better understand mechanisms regulating...

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Identifiers

PMID: 26819004
DOI: 10.1186/s13041-016-0190-x
PMCID: PMC4729175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Two di-leucine motifs regulate trafficking and function of mouse ASIC2a.PMID 26819004Read ↗

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