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Article

miR-23a, miR-146a and miR-301a confer predisposition to Vogt-Koyanagi-Harada syndrome but not to Behcet's disease.

Scientific reports - 28 Jan 2016

Hou Shengping, Ye Zi, Liao Dan, Bai Lin, Liu Yunjia, Zhang Jun, Kijlstra Aize, Yang Peizeng

Abstract excerpt

Ninety-eight miRNAs are involved in the immune response. However, the genetic roles of these miRNAs remain unclear in Behcet's disease (BD) and Vogt-Koyanagi-Harada (VKH) syndrome. This study aimed to explore the association and functional roles of copy number variants (CNV) in several miRNAs with BD and VKH syndrome. Genotyping of CNVs was examined by TaqMan PCR. The expression of miR-23a, transfection...

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PMID: 26818976
DOI: 10.1038/srep20057
PMCID: PMC4730241

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