Article
MicroRNA-146a and Ets-1 gene polymorphisms in ocular Behcet's disease and Vogt-Koyanagi-Harada syndrome.
Annals of the rheumatic diseases - 1 Jan 2014
Zhou Qingyun, Hou Shengping, Liang Liang, Li Xinyu, Tan Xiaoyu, Wei Lin, Lei Bo, Kijlstra Aize, Yang Peizeng
Abstract excerpt
AIM: MicroRNA-146a (miR-146a) is involved in certain immune-mediated diseases. Transcription factor Ets-1 strongly affects miR-146a promoter activity and directly regulates miR-146a expression. This study was performed to investigate the association of miR-146a and Ets-1 gene polymorphisms with Behçet's disease (BD) and Vogt-Koyanagi-Harada (VKH) disease in a Chinese Han population. METHODS: A total of 809...
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