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A functional variant of pre-miRNA-196a2 confers risk for Behcet's disease but not for Vogt-Koyanagi-Harada syndrome or AAU in ankylosing spondylitis.

Human genetics - 1 Dec 2013

Qi Jian, Hou Shengping, Zhang Qi, Liao Dan, Wei Lin, Fang Jing, Zhou Yan, Kijlstra Aize, Yang Peizeng

Abstract excerpt

This study aimed to investigate the predisposition of common pre-miRNA SNPs with Behcet's disease (BD), Vogt-Koyanagi-Harada (VKH) syndrome and acute anterior uveitis (AAU) associated with ankylosing spondylitis (AS). A two-stage association study was carried out in 859 BD, 400 VKH syndrome, 209 AAU(+)AS(+) patients and 1,685 controls all belonging to a Chinese Han population. Genotyping, the expression of...

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PMID: 23928854
DOI: 10.1007/s00439-013-1346-8

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