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Article

In Silico Screening and Molecular Dynamic Study of Nonsynonymous Single Nucleotide Polymorphisms Associated with Kidney Stones in the SLC26A6 Gene.

The Journal of urology - 1 Jul 2016

Lu Xiuli, Sun Deliang, Xu Bo, Pan Jichuan, Wei Yanhong, Mao Xu, Yu Daojun, Liu Hongsheng, Gao Bing

Abstract excerpt

PURPOSE: SLC26A6 is a multifunctional anion transporter with a critical physiological role in the transport of oxalate anions. Recognizing a genetic variant of SLC26A6 would advance our understanding of oxalate transport in the formation of calcium oxalate stones. MATERIALS AND METHODS: All nsSNPs (nonsynonymous single nucleotide polymorphisms) reported in human SLC26A6 were investigated using 4 in silico tools,...

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PMID: 26812303
DOI: 10.1016/j.juro.2016.01.093

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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