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Article

Two second-site mutations compensate the engineered mutation of R7A in vesicular stomatitis virus nucleocapsid protein.

Virus research - 2 Mar 2016

Chen Longyun, Zhong Yi, Hu Zhulong, Qin Yali, Chen Mingzhou

Abstract excerpt

The functional template for the transcription and replication of vesicular stomatitis virus (VSV) is genomic RNA encapsidated by nucleocapsid (N) protein. Previous studies showed that the amino acid R7 in the N-terminal arm of N is involved in N-N interaction in the N-RNA complex. In our study, the recombinant virus with mutation of R7A (rVSV(R7A)) in N was recovered, and the replication level of passage 1 (P1)...

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PMID: 26811905
DOI: 10.1016/j.virusres.2016.01.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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